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What the FDA labels say about taking them together

Etoposide and warfarin

Etoposide's FDA label (Etopophos) of July 31, 2026 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name etoposide.

Check it at the source: the etoposide FDA label on DailyMed (effective September 14, 2023, Hikma Pharmaceuticals USA Inc.); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the etoposide label say about warfarin?

Etopophos label (H2-Pharma, LLC, July 31, 2026), drug interactions

DRUG INTERACTIONS Warfarin: Co-administration of ETOPOPHOS with warfarin can result in elevated international normalized ratio (INR).

Source: FDA drug label (Etopophos, NDA020457), H2-Pharma, LLC, effective July 31, 2026 (SPL set 7499fc35-fae8-44ad-bbab-9a1a589bf3ee), via openFDA

Source: FDA drug label (Etoposide), Hikma Pharmaceuticals USA Inc., effective September 14, 2023 (SPL set 6dfedeff-a807-4405-a482-2f7109ad31c9), via openFDA; the full label on DailyMed

What does the warfarin label say about etoposide?

Warfarin's label (effective May 29, 2026) does not name etoposide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

6Etoposide generic labelers
19Warfarin generic labelers
EtoposideWarfarin
Labeled forLung cancerBlood clots (DVT and PE), Atrial fibrillation
Boxed warningYesYes
Pharmacy cost (NADAC)n/a$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?