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What the FDA labels say about taking them together

Carbamazepine and etonogestrel

Etonogestrel's FDA label of May 28, 2026 names carbamazepine in its drug interactions section; the carbamazepine labels PlainMeds reads (3) do not name etonogestrel. The etonogestrel label: “Some drugs or herbal products that may decrease the effectiveness of HCs include efavirenz, phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampicin, topiramate, rifabutin …”

Check it at the source: the carbamazepine FDA label on DailyMed (effective August 20, 2026, Novartis Pharmaceuticals Corporation); the etonogestrel FDA label on DailyMed (effective May 28, 2026, Organon LLC).

What does the carbamazepine label say about etonogestrel?

Carbamazepine's label (effective August 20, 2026) and its 2 other brand-application labels do not name etonogestrel in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Tegretol), Novartis Pharmaceuticals Corporation, effective August 20, 2026 (SPL set 8d409411-aa9f-4f3a-a52c-fbcb0c3ec053), via openFDA; the full label on DailyMed

What does the etonogestrel label say about carbamazepine?

Etonogestrel label, drug interactions

Some drugs or herbal products that may decrease the effectiveness of HCs include efavirenz, phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampicin, topiramate, rifabutin, rufinamide, aprepitant, and products containing St. John's wort.

Source: FDA drug label (Nexplanon), Organon LLC, effective May 28, 2026 (SPL set 487f8a62-e142-457c-97cc-2e398fde7594), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

42Carbamazepine generic labelers
0Etonogestrel generic labelers
CarbamazepineEtonogestrel
Labeled forBipolar disorder, Seizures and epilepsyBirth control
Boxed warningYesYes
Pharmacy cost (NADAC)$0.119 per tablet 200 mg tabletn/a
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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