What the FDA labels say about taking them together
Ethinyl estradiol/norgestimate and voriconazole
Ethinyl estradiol/norgestimate's FDA label of February 6, 2026 names voriconazole in its drug interactions section; the voriconazole labels PlainMeds reads (3) do not name ethinyl estradiol/norgestimate. The ethinyl estradiol/norgestimate label: “CYP3A4 inhibitors such as itraconazole, voriconazole, fluconazole, grapefruit juice, or ketoconazole may increase plasma hormone concentrations.”
Check it at the source: the ethinyl estradiol/norgestimate FDA label on DailyMed (effective February 6, 2026, Glenmark Pharmaceuticals Inc., USA); the voriconazole FDA label on DailyMed (effective February 26, 2026, Roerig).
What does the ethinyl estradiol/norgestimate label say about voriconazole?
Ethinyl estradiol/norgestimate label, drug interactionsCYP3A4 inhibitors such as itraconazole, voriconazole, fluconazole, grapefruit juice, or ketoconazole may increase plasma hormone concentrations.
Source: FDA drug label (Norgestimate and Ethinyl Estradiol), Glenmark Pharmaceuticals Inc., USA, effective February 6, 2026 (SPL set 8b247e46-203e-4f5b-b5a7-cbd57341c735), via openFDA; the full label on DailyMed
What does the voriconazole label say about ethinyl estradiol/norgestimate?
Voriconazole's label (effective February 26, 2026) and its 2 other brand-application labels do not name ethinyl estradiol/norgestimate in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (VFEND), NDA021630 (Pf Prism Cv), as published by Roerig, effective February 26, 2026 (SPL set ce3ef5cf-3087-4d92-9d94-9eb8287228db), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ethinyl estradiol/norgestimate | Voriconazole | |
|---|---|---|
| Labeled for | Acne, Birth control | Fungal infections |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.115 per tablet 0.25-0.035 mg tablet | $1.88 per tablet 200 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once