What the FDA labels say about taking them together
Ethacrynic acid and streptomycin
Streptomycin's FDA label of January 21, 2026 names ethacrynic acid in its drug interactions section; the ethacrynic acid label PlainMeds reads does not name streptomycin.
Check it at the source: the ethacrynic acid FDA label on DailyMed (effective August 31, 2020, Bausch Health US, LLC); the streptomycin FDA label on DailyMed (effective January 21, 2026, XGen Pharmaceuticals DJB, Inc.).
What does the ethacrynic acid label say about streptomycin?
Ethacrynic acid's label (effective August 31, 2020) does not name streptomycin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (EDECRIN), Bausch Health US, LLC, effective August 31, 2020 (SPL set 1efe378e-fee1-4ae9-8ea5-0fe2265fe2d8), via openFDA; the full label on DailyMed
What does the streptomycin label say about ethacrynic acid?
Streptomycin label, drug interactionsDrug Interactions The ototoxic effects of the aminoglycosides, including streptomycin, are potentiated by the coadministration of ethacrynic acid, furosemide, mannitol and possibly other diuretics.
Source: FDA drug label (Streptomycin), XGen Pharmaceuticals DJB, Inc., effective January 21, 2026 (SPL set abd1f64e-4283-4370-aae8-3666316aa36e), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ethacrynic acid | Streptomycin | |
|---|---|---|
| Labeled for | Edema (fluid retention), Heart failure | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.807 per tablet 25 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once