What the FDA labels say about taking them together
Ethacrynic acid and neomycin
Neomycin's FDA label of February 12, 2026 names ethacrynic acid in its boxed warning (prescription label) section; the ethacrynic acid label PlainMeds reads does not name neomycin.
Check it at the source: the ethacrynic acid FDA label on DailyMed (effective August 31, 2020, Bausch Health US, LLC); the neomycin FDA label on DailyMed (effective February 12, 2026).
What does the ethacrynic acid label say about neomycin?
Ethacrynic acid's label (effective August 31, 2020) does not name neomycin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (EDECRIN), Bausch Health US, LLC, effective August 31, 2020 (SPL set 1efe378e-fee1-4ae9-8ea5-0fe2265fe2d8), via openFDA; the full label on DailyMed
What does the neomycin label say about ethacrynic acid?
Neomycin label, boxed warning (prescription label)The concurrent use of neomycin with potent diuretics such as ethacrynic acid or furosemide should be avoided, since certain diuretics by themselves may cause ototoxicity.
Source: FDA drug label (Neomycin Sulfate), Aldermed Inc., effective February 12, 2026 (SPL set 4978bb06-8b7c-9a44-e063-6294a90ac4cf), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ethacrynic acid | Neomycin | |
|---|---|---|
| Labeled for | Edema (fluid retention), Heart failure | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.807 per tablet 25 mg tablet | $0.833 per tablet 500 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once