What the FDA labels say about taking them together
Esomeprazole and pazopanib
Pazopanib's FDA label of December 16, 2025 names esomeprazole in its drug interactions section; the esomeprazole labels PlainMeds reads (3) do not name pazopanib. The pazopanib label: “Concomitant use of VOTRIENT with esomeprazole, a PPI, decreased the exposure of pazopanib.”
Check it at the source: the esomeprazole FDA label on DailyMed (effective March 19, 2024, Haleon US Holdings LLC); the pazopanib FDA label on DailyMed (effective December 16, 2025, Novartis Pharmaceuticals Corporation).
What does the esomeprazole label say about pazopanib?
Esomeprazole's label (effective March 19, 2024) and its 2 other brand-application labels do not name pazopanib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Nexium 24HR), NDA204655 (Astrazeneca Lp), as published by Haleon US Holdings LLC, effective March 19, 2024 (SPL set 4513934d-0cf0-40fc-a348-b4e75a33b094), via openFDA; the full label on DailyMed
What does the pazopanib label say about esomeprazole?
Pazopanib label, drug interactionsConcomitant use of VOTRIENT with esomeprazole, a PPI, decreased the exposure of pazopanib.
Source: FDA drug label (VOTRIENT), Novartis Pharmaceuticals Corporation, effective December 16, 2025 (SPL set eeaaaf38-fb86-4d9f-a19d-0f61daac2fd7), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Esomeprazole | Pazopanib | |
|---|---|---|
| Labeled for | Acid reflux and ulcers | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.145 per capsule 20 mg capsule | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once