Skip to main content

What the FDA labels say about taking them together

Erlotinib and voriconazole

Erlotinib's FDA label of June 10, 2024 names voriconazole in its drug interactions section; the voriconazole labels PlainMeds reads (3) do not name erlotinib. The erlotinib label: “Avoid co-administering erlotinib with strong CYP3A4 inhibitors or a combined CYP3A4 and CYP1A2 inhibitor (e.g., ciprofloxacin).”

Check it at the source: the erlotinib FDA label on DailyMed (effective June 10, 2024, Alembic Pharmaceuticals Limited); the voriconazole FDA label on DailyMed (effective February 26, 2026, Roerig).

What does the erlotinib label say about voriconazole?

Erlotinib label, drug interactions

Avoid co-administering erlotinib with strong CYP3A4 inhibitors (e.g., boceprevir, clarithromycin, conivaptan, indinavir, itraconazole, ketoconazole, lopinavir/ritonavir, nefazodone, nelfinavir, posaconazole, ritonavir, saquinavir, telithromycin, voriconazole, grapefruit or grapefruit juice) or a combined CYP3A4 and CYP1A2 inhibitor (e.g., ciprofloxacin).

Source: FDA drug label (ERLOTINIB HYDROCHLORIDE), Alembic Pharmaceuticals Limited, effective June 10, 2024 (SPL set ab6f3cb3-34a8-4492-a5d7-fb6b055a2d6b), via openFDA; the full label on DailyMed

What does the voriconazole label say about erlotinib?

Voriconazole's label (effective February 26, 2026) and its 2 other brand-application labels do not name erlotinib in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (VFEND), NDA021630 (Pf Prism Cv), as published by Roerig, effective February 26, 2026 (SPL set ce3ef5cf-3087-4d92-9d94-9eb8287228db), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

10Erlotinib generic labelers
31Voriconazole generic labelers
ErlotinibVoriconazole
Labeled forLung cancerFungal infections
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$1.88 per tablet 200 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?