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What the FDA labels say about taking them together

Eltrombopag and valsartan

Eltrombopag's FDA label of December 18, 2025 names valsartan in its drug interactions section; the valsartan labels PlainMeds reads (2) do not name eltrombopag.

Check it at the source: the eltrombopag FDA label on DailyMed (effective December 18, 2025, Novartis Pharmaceuticals Corporation); the valsartan FDA label on DailyMed (effective August 5, 2026, Macleods Pharmaceuticals Limited).

What does the eltrombopag label say about valsartan?

Eltrombopag label, drug interactions

Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., atorvastatin, bosentan, ezetimibe, fluvastatin, glyburide, olmesartan, pitavastatin, pravastatin, rosuvastatin, repaglinide, rifampin, simvastatin acid, SN-38 [active metabolite of irinotecan], valsartan) or breast cancer resistance protein (BCRP) (e.g., imatinib, irinotecan, lapatinib, methotrexate, mitoxantrone, rosuvastatin, sulfasalazine, topotecan).

Source: FDA drug label (Alvaiz, NDA216774), Teva Pharmaceuticals, Inc., effective January 1, 2026 (SPL set ed51e463-7a03-4858-bbd2-882ce4753d5a), via openFDA

Source: FDA drug label (PROMACTA), Novartis Pharmaceuticals Corporation, effective December 18, 2025 (SPL set 7714a0ed-34bb-46e6-a0a5-b363908b22c2), via openFDA; the full label on DailyMed

What does the valsartan label say about eltrombopag?

Valsartan's label (effective August 5, 2026) and its 1 other brand-application label do not name eltrombopag in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Valsartan), Macleods Pharmaceuticals Limited, effective August 5, 2026 (SPL set 251ccff4-bf86-453b-9d1c-e3c1ecfd3a46), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

13Eltrombopag generic labelers
34Valsartan generic labelers
EltrombopagValsartan
Labeled forAnemiaHigh blood pressure, Heart failure
Boxed warningYesYes
Pharmacy cost (NADAC)$25.85 per tablet 50 mg tablet$0.0963 per tablet 40 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?