What the FDA labels say about taking them together
Elbasvir/grazoprevir and phenytoin
Elbasvir/grazoprevir's FDA label of March 13, 2026 names phenytoin in its contraindications section; the phenytoin labels PlainMeds reads (2) do not name elbasvir/grazoprevir.
Check it at the source: the elbasvir/grazoprevir FDA label on DailyMed (effective March 13, 2026, Merck Sharp & Dohme LLC); the phenytoin FDA label on DailyMed (effective October 15, 2024, Mylan Pharmaceuticals Inc.).
What does the elbasvir/grazoprevir label say about phenytoin?
Elbasvir/grazoprevir label, contraindicationsNamed in a table that the FDA label file prints without its column breaks; the full label shows the table.
Source: FDA drug label (ZEPATIER), Merck Sharp & Dohme LLC, effective March 13, 2026 (SPL set 164dc02a-9180-426a-b8b5-04ab39d2bbd4), via openFDA; the full label on DailyMed
What does the phenytoin label say about elbasvir/grazoprevir?
Phenytoin's label (effective October 15, 2024) and its 1 other brand-application label do not name elbasvir/grazoprevir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Phenytek), Mylan Pharmaceuticals Inc., effective October 15, 2024 (SPL set 0f94c791-8b07-4b41-927e-c9f28bec5f60), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Elbasvir/grazoprevir | Phenytoin | |
|---|---|---|
| Labeled for | Hepatitis C | Seizures and epilepsy |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $0.145 per capsule 100 mg capsule |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once