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What the FDA labels say about taking them together

Econazole and warfarin

Econazole's FDA label of June 22, 2026 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name econazole.

Check it at the source: the econazole FDA label on DailyMed (effective June 22, 2026, Encube Ethicals, Inc.); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the econazole label say about warfarin?

Econazole label, drug interactions

Drug Interactions Warfarin Concomitant administration of econazole and warfarin has resulted in enhancement of anticoagulation effect.

Source: FDA drug label (Ecoza, NDA205175), Resilia Pharmaceuticals, Inc., effective December 4, 2023 (SPL set 0bb5fa27-32ed-ed13-e063-6394a90a1577), via openFDA

Source: FDA drug label (Econazole Nitrate), Encube Ethicals, Inc., effective June 22, 2026 (SPL set 64d82b8b-d749-4bfe-ba3e-25836d54e115), via openFDA; the full label on DailyMed

What does the warfarin label say about econazole?

Warfarin's label (effective May 29, 2026) does not name econazole in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

6Econazole generic labelers
19Warfarin generic labelers
EconazoleWarfarin
Labeled forFungal infectionsBlood clots (DVT and PE), Atrial fibrillation
Boxed warningNoYes
Pharmacy cost (NADAC)$0.351 per gram 1% cream$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?