What the FDA labels say about taking them together
Echothiophate and succinylcholine
Echothiophate's FDA label of July 7, 2025 names succinylcholine in its drug interactions section, and succinylcholine's label names echothiophate too.
Check it at the source: the echothiophate FDA label on DailyMed (effective July 7, 2025, Fera Pharmaceuticals, LLC); the succinylcholine FDA label on DailyMed (effective August 18, 2026, Hospira, Inc.).
What does the echothiophate label say about succinylcholine?
Echothiophate label, drug interactionsDrug Interactions Echothiophate iodide for ophthalmic solution potentiates other cholinesterase inhibitors such as succinylcholine or organophosphate and carbamate insecticides.
Echothiophate label, warningsWARNINGS Succinylcholine should be administered only with great caution, if at all, prior to or during general anesthesia to patients receiving anticholinesterase medication because of possible respiratory or cardiovascular collapse.
Source: FDA drug label (Phospholine Iodide), Fera Pharmaceuticals, LLC, effective July 7, 2025 (SPL set 8afc8951-db76-4f27-8752-7c0d6aa47244), via openFDA; the full label on DailyMed
What does the succinylcholine label say about echothiophate?
Succinylcholine label, warnings and precautionsPlasma cholinesterase activity may also be diminished by chronic administration of oral contraceptives, glucocorticoids, or certain monoamine oxidase inhibitors and by irreversible inhibitors of plasma cholinesterase (e.g., organophosphate insecticides, echothiophate, and certain antineoplastic drugs) [see Drug Interactions (7.1) ].
Source: FDA drug label (QUELICIN), Hospira, Inc., effective August 18, 2026 (SPL set fb08161e-7711-406d-e7b3-ea4515c07983), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Echothiophate | Succinylcholine | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | Listed; available | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once