What the FDA labels say about taking them together
Droxidopa and linezolid
Droxidopa's FDA label of July 1, 2019 names linezolid in its drug interactions section; the linezolid labels PlainMeds reads (3) do not name droxidopa. The droxidopa label: “However, based on mechanism of action, the use of non-selective MAO inhibitors and linezolid should be avoided as there is a potential for increased blood pressure when taken with NORTHERA.”
Check it at the source: the droxidopa FDA label on DailyMed (effective July 1, 2019, Lundbeck Pharmaceuticals LLC); the linezolid FDA label on DailyMed (effective June 19, 2026, Hospira, Inc.).
What does the droxidopa label say about linezolid?
Droxidopa label, drug interactionsHowever, based on mechanism of action, the use of non-selective MAO inhibitors and linezolid should be avoided as there is a potential for increased blood pressure when taken with NORTHERA.
Source: FDA drug label (Northera), Lundbeck Pharmaceuticals LLC, effective July 1, 2019 (SPL set 2179f02c-48d7-48eb-8007-5ae43d8d16bc), via openFDA; the full label on DailyMed
What does the linezolid label say about droxidopa?
Linezolid's label (effective June 19, 2026) and its 2 other brand-application labels do not name droxidopa in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Linezolid), Hospira, Inc., effective June 19, 2026 (SPL set c401f1a8-cc37-461b-bfef-f2e156629bf8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Droxidopa | Linezolid | |
|---|---|---|
| Labeled for | n/a | Bacterial infections |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.472 per capsule 100 mg capsule | $1.44 per tablet 600 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once