Drospirenone · more major-labeled pairs than Cholestyramine

SPL labels Drospirenone + Cholestyramine as minor; Drospirenone 29 / Cholestyramine 31 in that band.

Mechanism on file: Cholestyramine can prevent your body from properly absorbing folate from your food or vitamins.

FDA SPL severity: Minor

Drospirenone

Full Drospirenone label record

Combined Oral Contraceptive

Cholestyramine

Full Cholestyramine label record

Bile Acid Sequestrant

Drospirenone + Cholestyramine · SPL mechanism field

Cholestyramine can prevent your body from properly absorbing folate from your food or vitamins.

Minor band excerpt · Drospirenone with Cholestyramine

7.5 Effects of Other Drugs on Folates Several drugs have been reported to reduce folate concentrations by inhibition of the dihydrofolate reductase enzyme (e.g., methotrexate and sulfasalazine) or by reducing folate absorption (e.g., cholestyramine), or via unknown mechanisms (e.g., antiepileptics such as carbamazepine, phenytoin, phenobarbital, primidone and valproic acid).

Drospirenone · 1 major-labeled pairs (vs Cholestyramine's 0)

View all Drospirenone interactions →

Cholestyramine · 34 SPL pairs (broader portfolio than Drospirenone)

View all Cholestyramine interactions →

FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.