Carbamazepine · more major-labeled pairs than Drospirenone
SPL labels Drospirenone + Carbamazepine as minor; Drospirenone 29 / Carbamazepine 110 in that band.
Mechanism on file: Carbamazepine causes your body to break down birth control hormones too quickly. This can make the pill fail to prevent pregnancy and may also lower your folate levels.
FDA SPL severity: Minor
Drospirenone + Carbamazepine · SPL mechanism field
Carbamazepine causes your body to break down birth control hormones too quickly. This can make the pill fail to prevent pregnancy and may also lower your folate levels.
Minor band excerpt · Drospirenone with Carbamazepine
Some drugs or herbal products that may decrease the effectiveness of hormonal contraceptives include phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampin, topiramate and products containing St. 7.5 Effects of Other Drugs on Folates Several drugs have been reported to reduce folate concentrations by inhibition of the dihydrofolate reductase enzyme (e.g., methotrexate and sulfasalazine) or by reducing folate absorption (e.g., cholestyramine), or via unknown mechanisms (e.g., antiepileptics such as carbamazepine, phenytoin, phenobarbital,...
Drospirenone · 29 minor + 30 total pairs
- Acetaminophen minor
- Ascorbic Acid minor
- Atorvastatin minor
- Cholestyramine minor
Carbamazepine · 3 major-labeled pairs (vs Drospirenone's 1)
- Acetaminophen minor
- Acetaminophen/Oxycodone minor
- Albendazole minor
- Alprazolam minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.