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What the FDA labels say about taking them together

Dronedarone and verapamil

Dronedarone's FDA label of May 29, 2025 names verapamil in its drug interactions section; the verapamil labels PlainMeds reads (4) do not name dronedarone. The dronedarone label: “Calcium Channel Blockers Verapamil and diltiazem are moderate CYP3A inhibitors and increase dronedarone exposure.”

Check it at the source: the dronedarone FDA label on DailyMed (effective May 29, 2025, Sanofi-Aventis U.S. LLC); the verapamil FDA label on DailyMed (effective April 6, 2026, Zydus Pharmaceuticals (USA) Inc.).

What does the dronedarone label say about verapamil?

Dronedarone label, drug interactions

Calcium Channel Blockers Verapamil and diltiazem are moderate CYP3A inhibitors and increase dronedarone exposure.

Source: FDA drug label (Multaq), Sanofi-Aventis U.S. LLC, effective May 29, 2025 (SPL set 7fa41601-7fb5-4155-8e50-2ae903f0d2d6), via openFDA; the full label on DailyMed

What does the verapamil label say about dronedarone?

Verapamil's label (effective April 6, 2026) and its 3 other brand-application labels do not name dronedarone in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Verapamil hydrochloride), Zydus Pharmaceuticals (USA) Inc., effective April 6, 2026 (SPL set e19ab8d8-dae5-489d-9805-7e7407bea06d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Dronedarone generic labelers
43Verapamil generic labelers
DronedaroneVerapamil
Labeled forn/aHigh blood pressure, Atrial fibrillation, Angina
Boxed warningYesNo
Pharmacy cost (NADAC)$13.19 per tablet 400 mg tablet$0.191 per tablet 180 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?