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What the FDA labels say about taking them together

Amphotericin b and dronabinol

Dronabinol's FDA label of May 6, 2026 names amphotericin b in its drug interactions section; the amphotericin b label PlainMeds reads does not name dronabinol. The dronabinol label: “Potential for displacement of other drugs from plasma proteins; monitor for adverse reactions to concomitant narrow therapeutic index drugs when initiating or increasing the dosage of SYNDROS.”

Check it at the source: the amphotericin b FDA label on DailyMed (effective June 3, 2025, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.); the dronabinol FDA label on DailyMed (effective May 6, 2026, Ascend Laboratories, LLC).

What does the amphotericin b label say about dronabinol?

Amphotericin b's label (effective June 3, 2025) does not name dronabinol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Amphotericin B), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective June 3, 2025 (SPL set 2b2f3ff5-9d62-4ad2-8eac-1181e5911513), via openFDA; the full label on DailyMed

What does the dronabinol label say about amphotericin b?

Dronabinol label, drug interactions

Potential for displacement of other drugs from plasma proteins; monitor for adverse reactions to concomitant highly protein-bound drugs and narrow therapeutic index drugs (e.g., warfarin, cyclosporine, amphotericin B) when initiating or increasing the dosage of dronabinol capsules.

Source: FDA drug label (Syndros, NDA205525), Wellhouse Pharma, LLC, effective April 17, 2026 (SPL set 3cdcb4f5-5af9-4ff7-b535-2a5cf4c6da89), via openFDA

Source: FDA drug label (Dronabinol), NDA018651 (Alkem Labs Ltd), as published by Ascend Laboratories, LLC, effective May 6, 2026 (SPL set adb1801c-0fb5-4e16-b969-1db91230e0b9), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

5Amphotericin b generic labelers
1Dronabinol generic labelers
Amphotericin bDronabinol
Labeled forFungal infectionsn/a
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$3.35 per capsule 5 mg capsule
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?