What the FDA labels say about taking them together
Doxycycline and multiple vitamins
Multiple vitamins's FDA label of November 20, 2024 names doxycycline in its drug interactions section; the doxycycline labels PlainMeds reads (4) do not name multiple vitamins. The multiple vitamins label: “Thiamine, riboflavin, pyridoxine, niacinamide, and ascorbic acid decrease activities of erythromycin, kanamycin, streptomycin, doxycycline, and lincomycin”
Check it at the source: the doxycycline FDA label on DailyMed (effective July 25, 2025, Chartwell RX, LLC.); the multiple vitamins FDA label on DailyMed (effective November 20, 2024).
What does the doxycycline label say about multiple vitamins?
Doxycycline's label (effective July 25, 2025) and its 3 other brand-application labels do not name multiple vitamins in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Doxycycline Monohydrate), Chartwell RX, LLC., effective July 25, 2025 (SPL set 02aa8731-d40f-43d8-8b63-a79a0503f8db), via openFDA; the full label on DailyMed
What does the multiple vitamins label say about doxycycline?
Multiple vitamins label, drug interactionsEffect of INFUVITE PEDIATRIC on other drugs: Thiamine, riboflavin, pyridoxine, niacinamide, and ascorbic acid decrease activities of erythromycin, kanamycin, streptomycin, doxycycline, and lincomycin
Source: FDA drug label (Infuvite Adult, NDA021163), Sandoz Inc, effective November 6, 2024 (SPL set 14c7bfc5-07e8-400f-b8ff-5e4794dd2805), via openFDA
Source: FDA drug label (Infuvite Pediatric), Sandoz Inc, effective November 20, 2024 (SPL set 6d06546e-8b0a-4490-82d9-397bd902a044), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Doxycycline | Multiple vitamins | |
|---|---|---|
| Labeled for | Urinary tract infections, Bacterial infections, Acne | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.118 per tablet 100 mg tablet | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once