What the FDA labels say about taking them together
Doxazosin and prazosin
Doxazosin's FDA label of October 15, 2023 names prazosin in its contraindications section; the prazosin label PlainMeds reads does not name doxazosin. The doxazosin label: “CONTRAINDICATIONS The use of CARDURA is contraindicated in patients with a hypersensitivity to doxazosin, other quinazolines, or any of its components.”
Check it at the source: the doxazosin FDA label on DailyMed (effective October 15, 2023, Viatris Specialty LLC); the prazosin FDA label on DailyMed (effective March 6, 2026, Prasco Laboratories).
What does the doxazosin label say about prazosin?
Doxazosin label, contraindicationsCONTRAINDICATIONS The use of CARDURA is contraindicated in patients with a hypersensitivity to doxazosin, other quinazolines (e.g., prazosin, terazosin), or any of its components.
Source: FDA drug label (Cardura Xl, NDA021269), Viatris Specialty LLC, effective May 15, 2023 (SPL set 355bcdce-0481-48ba-8ebd-2009106aaf77), via openFDA
Source: FDA drug label (Cardura), Viatris Specialty LLC, effective October 15, 2023 (SPL set 5e1f5e49-2da1-43ab-9795-228a8bcc5a82), via openFDA; the full label on DailyMed
What does the prazosin label say about doxazosin?
Prazosin's label (effective March 6, 2026) does not name doxazosin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Prazosin Hydrochloride), NDA017442 (Pfizer), as published by Prasco Laboratories, effective March 6, 2026 (SPL set cbe89216-7dea-43d7-b12e-44ccfb69af3d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Doxazosin | Prazosin | |
|---|---|---|
| Labeled for | Enlarged prostate (BPH), High blood pressure | High blood pressure |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0752 per tablet 1 mg tablet | $0.0842 per capsule 1 mg capsule |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once