What the FDA labels say about taking them together
Doxazosin and nifedipine
Nifedipine's FDA label of December 24, 2024 names doxazosin in its drug interactions section; the doxazosin labels PlainMeds reads (2) do not name nifedipine. The nifedipine label: “Co-administration of nifedipine resulted in a decrease in AUC and C max of doxazosin to 83% and 86% of the values in the absence of nifedipine, respectively.”
Check it at the source: the doxazosin FDA label on DailyMed (effective October 15, 2023, Viatris Specialty LLC); the nifedipine FDA label on DailyMed (effective December 24, 2024, Aurobindo Pharma Limited).
What does the doxazosin label say about nifedipine?
Doxazosin's label (effective October 15, 2023) and its 1 other brand-application label do not name nifedipine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cardura), Viatris Specialty LLC, effective October 15, 2023 (SPL set 5e1f5e49-2da1-43ab-9795-228a8bcc5a82), via openFDA; the full label on DailyMed
What does the nifedipine label say about doxazosin?
Nifedipine label, drug interactionsCo-administration of nifedipine resulted in a decrease in AUC and C max of doxazosin to 83% and 86% of the values in the absence of nifedipine, respectively.
Source: FDA drug label (Nifedipine), Aurobindo Pharma Limited, effective December 24, 2024 (SPL set eb70b7ff-f9f0-41d0-901a-f4c04ae9ed46), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Doxazosin | Nifedipine | |
|---|---|---|
| Labeled for | Enlarged prostate (BPH), High blood pressure | High blood pressure, Angina |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0752 per tablet 1 mg tablet | $0.130 per tablet 30 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once