What the FDA labels say about taking them together
Dopamine and phenytoin
Dopamine's FDA label (Dopamine Hydrochloride And Dextrose) of November 11, 2020 names phenytoin in its drug interactions section; the phenytoin labels PlainMeds reads (2) do not name dopamine. The dopamine label: “Administration of phenytoin to patients receiving dopamine HCl has been reported to lead to hypotension and bradycardia.”
Check it at the source: the dopamine FDA label on DailyMed (effective May 12, 2026, Hospira, Inc.); the phenytoin FDA label on DailyMed (effective October 15, 2024, Mylan Pharmaceuticals Inc.).
What does the dopamine label say about phenytoin?
Dopamine Hydrochloride And Dextrose label (Baxter Healthcare Corporation, November 11, 2020), drug interactionsAdministration of phenytoin to patients receiving dopamine HCl has been reported to lead to hypotension and bradycardia.
Source: FDA drug label (Dopamine Hydrochloride And Dextrose, NDA019615), Baxter Healthcare Corporation, effective November 11, 2020 (SPL set cb97d4a0-89ed-407c-a763-209386b6f75c), via openFDA
Source: FDA drug label (Dopamine Hydrochloride in Dextrose), Hospira, Inc., effective May 12, 2026 (SPL set 08f23f6e-150d-45ea-098e-f2edf64c21a1), via openFDA; the full label on DailyMed
What does the phenytoin label say about dopamine?
Phenytoin's label (effective October 15, 2024) and its 1 other brand-application label do not name dopamine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Phenytek), Mylan Pharmaceuticals Inc., effective October 15, 2024 (SPL set 0f94c791-8b07-4b41-927e-c9f28bec5f60), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dopamine | Phenytoin | |
|---|---|---|
| Labeled for | n/a | Seizures and epilepsy |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.145 per capsule 100 mg capsule |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once