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What the FDA labels say about taking them together

Adenosine and dipyridamole

Adenosine's FDA label of April 14, 2025 names dipyridamole in its drug interactions section, and dipyridamole's label names adenosine too. The dipyridamole label: “Adenosinergic agents Dipyridamole has been reported to increase the plasma levels and cardiovascular effects of adenosine.”

Check it at the source: the adenosine FDA label on DailyMed (effective April 14, 2025, Meitheal Pharmaceuticals Inc.); the dipyridamole FDA label on DailyMed (effective September 16, 2023, Zydus Pharmaceuticals USA Inc.).

What does the adenosine label say about dipyridamole?

Adenosine label, drug interactions

DRUG INTERACTIONS Methylxanthines interfere with the activity of adenosine ( 7.1 , 10) Nucleoside transport inhibitors such as dipyridamole can increase the activity of adenosine

Source: FDA drug label (Adenosine), Meitheal Pharmaceuticals Inc., effective April 14, 2025 (SPL set b6851256-6cef-4f23-8129-19bb64380cd5), via openFDA; the full label on DailyMed

What does the dipyridamole label say about adenosine?

Dipyridamole label, drug interactions

Adenosinergic agents (e.g., adenosine, regadenoson) Dipyridamole has been reported to increase the plasma levels and cardiovascular effects of adenosine.

Source: FDA drug label (Dipyridamole), Zydus Pharmaceuticals USA Inc., effective September 16, 2023 (SPL set 004bada0-dbf7-4a94-8792-6833d7eeda2b), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

13Adenosine generic labelers
8Dipyridamole generic labelers
AdenosineDipyridamole
Labeled forn/an/a
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$0.236 per tablet 75 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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