What the FDA labels say about taking them together
Diltiazem and voclosporin
Voclosporin's FDA label of August 25, 2026 names diltiazem in its drug interactions section; the diltiazem labels PlainMeds reads (4) do not name voclosporin. The voclosporin label: “Reduce LUPKYNIS dosage when co-administered with moderate CYP3A4 inhibitors.”
Check it at the source: the diltiazem FDA label on DailyMed (effective August 7, 2026, Bausch Health US, LLC); the voclosporin FDA label on DailyMed (effective August 25, 2026, Aurinia Pharma U.S., Inc.).
What does the diltiazem label say about voclosporin?
Diltiazem's label (effective August 7, 2026) and its 3 other brand-application labels do not name voclosporin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (TIAZAC EXTENDED RELEASE), Bausch Health US, LLC, effective August 7, 2026 (SPL set c567fe7e-887e-4291-a0d1-2dd3f25cbf25), via openFDA; the full label on DailyMed
What does the voclosporin label say about diltiazem?
Voclosporin label, drug interactionsReduce LUPKYNIS dosage when co-administered with moderate CYP3A4 inhibitors (e.g., verapamil, fluconazole, diltiazem) [see Dosage and Administration ( 2.5 ].
Voclosporin label, warnings and precautionsCertain calcium-channel blocking agents (verapamil and diltiazem) may increase voclosporin blood concentrations and require dosage reduction of LUPKYNIS [see Dosage and Administration ( 2.5 ) and Drug Interactions ( 7.2 )].
Source: FDA drug label (LUPKYNIS), Aurinia Pharma U.S., Inc., effective August 25, 2026 (SPL set 9f489295-1156-52c7-5fd0-5c4c52f9b813), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Diltiazem | Voclosporin | |
|---|---|---|
| Labeled for | High blood pressure, Angina, Atrial fibrillation | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.144 per capsule 24h ER(cd) 120 mg capsule | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once