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What the FDA labels say about taking them together

Digoxin and thalidomide

Thalidomide's FDA label of March 24, 2023 names digoxin in its drug interactions section; the digoxin labels PlainMeds reads (3) do not name thalidomide.

Check it at the source: the digoxin FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.); the thalidomide FDA label on DailyMed (effective March 24, 2023, Celgene Corporation).

What does the digoxin label say about thalidomide?

Digoxin's label (effective December 5, 2024) and its 2 other brand-application labels do not name thalidomide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (LANOXIN), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set d91e3646-4c63-4512-ab22-db39c085c4dc), via openFDA; the full label on DailyMed

What does the thalidomide label say about digoxin?

Thalidomide label, drug interactions

Cardiovascular medications which may cause bradycardia include calcium channel blockers, beta blockers, alpha/beta-adrenergic blockers, and digoxin.

Source: FDA drug label (Thalomid), NDA020785 (Bristol-Myers), as published by Celgene Corporation, effective March 24, 2023 (SPL set 2eda833b-1357-4ed4-a093-194524fcb061), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

26Digoxin generic labelers
0Thalidomide generic labelers
DigoxinThalidomide
Labeled forHeart failure, Atrial fibrillationLeukemia, lymphoma and myeloma
Boxed warningNoYes
Pharmacy cost (NADAC)$0.133 per tablet 125 mcg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?