What the FDA labels say about taking them together
Digoxin and pacritinib
Pacritinib's FDA label of July 30, 2026 names digoxin in its drug interactions section; the digoxin labels PlainMeds reads (3) do not name pacritinib. The pacritinib label: “Measure serum digoxin concentrations before initiating concomitant use with VONJO and continue monitoring serum digoxin concentrations as recommended in the Prescribing Information for digoxin.”
Check it at the source: the digoxin FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.); the pacritinib FDA label on DailyMed (effective July 30, 2026, Sobi, Inc.).
What does the digoxin label say about pacritinib?
Digoxin's label (effective December 5, 2024) and its 2 other brand-application labels do not name pacritinib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (LANOXIN), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set d91e3646-4c63-4512-ab22-db39c085c4dc), via openFDA; the full label on DailyMed
What does the pacritinib label say about digoxin?
Pacritinib label, drug interactionsMeasure serum digoxin concentrations before initiating concomitant use with VONJO and continue monitoring serum digoxin concentrations as recommended in the Prescribing Information for digoxin [see Clinical Pharmacology ( 12.3 )].
Source: FDA drug label (Vonjo), Sobi, Inc., effective July 30, 2026 (SPL set 4b5ab444-0e1a-4984-99db-76ad11a298ee), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Digoxin | Pacritinib | |
|---|---|---|
| Labeled for | Heart failure, Atrial fibrillation | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.133 per tablet 125 mcg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once