What the FDA labels say about taking them together
Digoxin and octreotide
Octreotide's FDA label (Mycapssa) of July 24, 2025 names digoxin in its drug interactions section; the digoxin labels PlainMeds reads (3) do not name octreotide. The octreotide label: “Digoxin: exposure may be decreased and assessment of clinical response to digoxin should be performed ( 7 ).”
Check it at the source: the digoxin FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.); the octreotide FDA label on DailyMed (effective July 22, 2026, Novartis Pharmaceuticals Corporation).
What does the digoxin label say about octreotide?
Digoxin's label (effective December 5, 2024) and its 2 other brand-application labels do not name octreotide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (LANOXIN), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set d91e3646-4c63-4512-ab22-db39c085c4dc), via openFDA; the full label on DailyMed
What does the octreotide label say about digoxin?
Mycapssa label (Chiesi USA, Inc., July 24, 2025), drug interactionsDigoxin: exposure may be decreased and assessment of clinical response to digoxin should be performed ( 7 ).
Source: FDA drug label (Mycapssa, NDA208232), Chiesi USA, Inc., effective July 24, 2025 (SPL set 58d80bc6-bdfb-4908-93e7-aace447c8d1a), via openFDA
Source: FDA drug label (Sandostatin), Novartis Pharmaceuticals Corporation, effective July 22, 2026 (SPL set 4e2c9856-1836-49f0-9472-4dbeeb408f39), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Digoxin | Octreotide | |
|---|---|---|
| Labeled for | Heart failure, Atrial fibrillation | Diarrhea |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.133 per tablet 125 mcg tablet | $2.53 per mL 100 mcg/mL vial |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once