What the FDA labels say about taking them together
Digoxin and mavorixafor
Mavorixafor's FDA label of November 12, 2024 names digoxin in its drug interactions section; the digoxin labels PlainMeds reads (3) do not name mavorixafor. The mavorixafor label: “Measure serum digoxin concentrations before initiating concomitant use with XOLREMDI, and continue monitoring serum digoxin concentrations as recommended in the Prescribing Information for digoxin. …”
Check it at the source: the digoxin FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.); the mavorixafor FDA label on DailyMed (effective November 12, 2024, X4 Pharmaceuticals, Inc.).
What does the digoxin label say about mavorixafor?
Digoxin's label (effective December 5, 2024) and its 2 other brand-application labels do not name mavorixafor in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (LANOXIN), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set d91e3646-4c63-4512-ab22-db39c085c4dc), via openFDA; the full label on DailyMed
What does the mavorixafor label say about digoxin?
Mavorixafor label, drug interactionsMeasure serum digoxin concentrations before initiating concomitant use with XOLREMDI, and continue monitoring serum digoxin concentrations as recommended in the Prescribing Information for digoxin [see Clinical Pharmacology (12.3) ]. Mavorixafor is an inhibitor of P-gp.
Source: FDA drug label (XOLREMDI), NDA218709 (X4 Pharms), as published by X4 Pharmaceuticals, Inc., effective November 12, 2024 (SPL set 7f3a5ee3-ca73-4876-85a0-ed1e108a2237), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Digoxin | Mavorixafor | |
|---|---|---|
| Labeled for | Heart failure, Atrial fibrillation | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.133 per tablet 125 mcg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once