What the FDA labels say about taking them together
Digoxin and levalbuterol
Levalbuterol's FDA label of December 10, 2025 names digoxin in its drug interactions section; the digoxin labels PlainMeds reads (3) do not name levalbuterol. The levalbuterol label: “Consider monitoring potassium levels. Digoxin: May decrease serum digoxin levels.”
Check it at the source: the digoxin FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.); the levalbuterol FDA label on DailyMed (effective December 10, 2025, Ritedose Pharmaceuticals, LLC).
What does the digoxin label say about levalbuterol?
Digoxin's label (effective December 5, 2024) and its 2 other brand-application labels do not name levalbuterol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (LANOXIN), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set d91e3646-4c63-4512-ab22-db39c085c4dc), via openFDA; the full label on DailyMed
What does the levalbuterol label say about digoxin?
Levalbuterol label, drug interactionsConsider monitoring potassium levels. ( 7.3 ) Digoxin: May decrease serum digoxin levels.
Source: FDA drug label (Xopenex Hfa, NDA021730), Lupin Pharmaceuticals, Inc., effective June 2, 2025 (SPL set 70a35706-d7a8-4a48-98c6-1cab1c42fe8d), via openFDA
Source: FDA drug label (Levalbuterol), Ritedose Pharmaceuticals, LLC, effective December 10, 2025 (SPL set d6998949-e1cb-4c86-a480-c0dfd9cb75b5), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Digoxin | Levalbuterol | |
|---|---|---|
| Labeled for | Heart failure, Atrial fibrillation | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.133 per tablet 125 mcg tablet | $0.262 per mL 0.31 mg/3 mL solution |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once