What the FDA labels say about taking them together
Digoxin and lenalidomide
Lenalidomide's FDA label of March 24, 2023 names digoxin in its drug interactions section; the digoxin labels PlainMeds reads (3) do not name lenalidomide. The lenalidomide label: “Monitor digoxin plasma levels periodically due to increased C max and AUC with concomitant REVLIMID therapy.”
Check it at the source: the digoxin FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.); the lenalidomide FDA label on DailyMed (effective March 24, 2023, Celgene Corporation).
What does the digoxin label say about lenalidomide?
Digoxin's label (effective December 5, 2024) and its 2 other brand-application labels do not name lenalidomide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (LANOXIN), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set d91e3646-4c63-4512-ab22-db39c085c4dc), via openFDA; the full label on DailyMed
What does the lenalidomide label say about digoxin?
Lenalidomide label, drug interactionsMonitor digoxin plasma levels periodically due to increased C max and AUC with concomitant REVLIMID therapy ( 7.1 ).
Source: FDA drug label (Revlimid), NDA021880 (Bristol Myers Squibb), as published by Celgene Corporation, effective March 24, 2023 (SPL set 5fa97bf5-28a2-48f1-8955-f56012d296be), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Digoxin | Lenalidomide | |
|---|---|---|
| Labeled for | Heart failure, Atrial fibrillation | Leukemia, lymphoma and myeloma, Anemia |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.133 per tablet 125 mcg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once