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What the FDA labels say about taking them together

Digoxin and eliglustat

Eliglustat's FDA label of March 3, 2024 names digoxin in its drug interactions section; the digoxin labels PlainMeds reads (3) do not name eliglustat. The eliglustat label: “Prevention or Management; Digoxin; Monitor serum digoxin concentrations before initiating CERDELGA. Reduce digoxin dose by 30% and continue monitoring.”

Check it at the source: the digoxin FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.); the eliglustat FDA label on DailyMed (effective March 3, 2024, Genzyme Corporation).

What does the digoxin label say about eliglustat?

Digoxin's label (effective December 5, 2024) and its 2 other brand-application labels do not name eliglustat in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (LANOXIN), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set d91e3646-4c63-4512-ab22-db39c085c4dc), via openFDA; the full label on DailyMed

What does the eliglustat label say about digoxin?

Eliglustat label, drug interactions

Prevention or Management; Digoxin; Monitor serum digoxin concentrations before initiating CERDELGA. Reduce digoxin dose by 30% and continue monitoring.

Source: FDA drug label (Cerdelga), Genzyme Corporation, effective March 3, 2024 (SPL set 819f828a-b888-4e46-83fc-94d774a28a83), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

26Digoxin generic labelers
0Eliglustat generic labelers
DigoxinEliglustat
Labeled forHeart failure, Atrial fibrillationn/a
Boxed warningNoNo
Pharmacy cost (NADAC)$0.133 per tablet 125 mcg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?