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What the FDA labels say about taking them together

Dextran 40 and warfarin

Dextran 40's FDA label of May 22, 2026 names warfarin in its contraindications section; the warfarin label PlainMeds reads does not name dextran 40. The dextran 40 label: “… hemostatic defects of all types including those caused by drugs (heparin, warfarin, etc.), marked cardiac decompensation and in renal disease with severe oliguria or anuria.”

Check it at the source: the dextran 40 FDA label on DailyMed (effective May 22, 2026); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the dextran 40 label say about warfarin?

Dextran 40 label, contraindications

CONTRAINDICATIONS LMD (dextran 40) is contraindicated in patients with known hypersensitivity to dextran, in those with marked hemostatic defects of all types (thrombocytopenia, hypofibrinogenemia, etc.) including those caused by drugs (heparin, warfarin, etc.), marked cardiac decompensation and in renal disease with severe oliguria or anuria.

Source: FDA drug label (LMD in Dextrose), Hospira, Inc., effective May 22, 2026 (SPL set 3c273512-84e2-2cea-b201-12345a6bd1fe), via openFDA; the full label on DailyMed

What does the warfarin label say about dextran 40?

Warfarin's label (effective May 29, 2026) does not name dextran 40 in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Dextran 40 generic labelers
19Warfarin generic labelers
Dextran 40Warfarin
Labeled forBlood clots (DVT and PE)Blood clots (DVT and PE), Atrial fibrillation
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?