Desmopressin and Carbamazepine Interaction
Drug interaction information between Desmopressin and Carbamazepine.
Desmopressin and Carbamazepine have a documented moderate interaction in FDA labeling.
FDA drug labeling documents a moderate-severity interaction between Desmopressin and Carbamazepine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Carbamazepine can increase the effects of desmopressin, which may cause your body to hold onto too much water. This can lead to a dangerous drop in the salt levels in your blood.
FDA Label Information
tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, NSAIDs, lamotrigine and carbamazepine) should be performed with caution.
Desmopressin Also Interacts With
- Lamotrigine moderate
- Chlorpromazine moderate
Carbamazepine Also Interacts With
- Nirmatrelvir/Ritonavir major
- Ranolazine major
- Risperidone major
- Lithium moderate
- Apixaban moderate
Frequently Asked Questions
What SPL severity band is on file for Desmopressin + Carbamazepine?
Compiled FDA labeling labels this pair moderate. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Carbamazepine has 129 labeled pairs on file vs Desmopressin's 3. In the moderate band specifically: Desmopressin has 3 (also Lamotrigine, Chlorpromazine); Carbamazepine has 16 (also Lithium, Apixaban, Dronedarone, Fluconazole).
What mechanism field is on file for Desmopressin and Carbamazepine?
Carbamazepine can increase the effects of desmopressin, which may cause your body to hold onto too much water. This can lead to a dangerous drop in the salt levels in your blood.
Carbamazepine carries more major-labeled pairs than Desmopressin
SPL source-record counts only. This page's band is moderate · classes on file: Desmopressin (Vasopressin Analog); Carbamazepine (Anticonvulsant).
Carbamazepine has 3 major-labeled pairs vs Desmopressin's 0. This page itself is in the moderate band, not the major band.
0 major · 3 moderate · 0 minor · 3 total
- Other moderate peers for Desmopressin
- Lamotrigine
- Chlorpromazine
3 major · 16 moderate · 110 minor · 129 total
- Other moderate peers for Carbamazepine
- Lithium
- Apixaban
- Dronedarone
- Fluconazole
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.