What the FDA labels say about taking them together
Darunavir and nicardipine
Darunavir's FDA label of August 29, 2025 names nicardipine in its drug interactions section; the nicardipine labels PlainMeds reads (2) do not name darunavir. The darunavir label: “Clinical monitoring of patients is recommended.”
Check it at the source: the darunavir FDA label on DailyMed (effective August 29, 2025, Janssen Products LP); the nicardipine FDA label on DailyMed (effective August 24, 2024, Hikma Pharmaceuticals USA Inc.).
What does the darunavir label say about nicardipine?
Darunavir label, drug interactionsConcomitant Drug Class Drug Name Examples: Calcium Channel Blockers: amlodipine, diltiazem, felodipine, nicardipine, nifedipine, verapamil; Effect on Concentration of Darunavir Or Concomitant Drug: ↑ calcium channel blockers; Clinical Comment: Clinical monitoring of patients is recommended.
Source: FDA drug label (PREZISTA), Janssen Products LP, effective August 29, 2025 (SPL set 814301f9-c990-46a5-b481-2879a521a16f), via openFDA; the full label on DailyMed
What does the nicardipine label say about darunavir?
Nicardipine's label (effective August 24, 2024) and its 1 other brand-application label do not name darunavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Nicardipine Hydrochloride), Hikma Pharmaceuticals USA Inc., effective August 24, 2024 (SPL set 18fb1c2b-0c1e-436c-a5b6-d4840b5da228), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Darunavir | Nicardipine | |
|---|---|---|
| Labeled for | HIV | High blood pressure, Angina |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $1.16 per tablet 600 mg tablet | $1.12 per capsule 20 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once