What the FDA labels say about taking them together
Darunavir and felodipine
Darunavir's FDA label of August 29, 2025 names felodipine in its drug interactions section; the felodipine label PlainMeds reads does not name darunavir. The darunavir label: “Clinical monitoring of patients is recommended.”
Check it at the source: the darunavir FDA label on DailyMed (effective August 29, 2025, Janssen Products LP); the felodipine FDA label on DailyMed (effective August 11, 2026, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.).
What does the darunavir label say about felodipine?
Darunavir label, drug interactionsConcomitant Drug Class Drug Name Examples: Calcium Channel Blockers: amlodipine, diltiazem, felodipine, nicardipine, nifedipine, verapamil; Effect on Concentration of Darunavir Or Concomitant Drug: ↑ calcium channel blockers; Clinical Comment: Clinical monitoring of patients is recommended.
Source: FDA drug label (PREZISTA), Janssen Products LP, effective August 29, 2025 (SPL set 814301f9-c990-46a5-b481-2879a521a16f), via openFDA; the full label on DailyMed
What does the felodipine label say about darunavir?
Felodipine's label (effective August 11, 2026) does not name darunavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (FELODIPINE), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective August 11, 2026 (SPL set 0bef7cf2-012b-4804-ac93-0a8b333035db), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Darunavir | Felodipine | |
|---|---|---|
| Labeled for | HIV | High blood pressure |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $1.16 per tablet 600 mg tablet | $0.123 per tablet 5 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once