What the FDA labels say about taking them together
Darifenacin and verapamil
Darifenacin's FDA label of February 10, 2026 names verapamil in its drug interactions section; the verapamil labels PlainMeds reads (4) do not name darifenacin. The darifenacin label: “No dosing adjustments are recommended in the presence of moderate CYP3A4 inhibitors.”
Check it at the source: the darifenacin FDA label on DailyMed (effective February 10, 2026, Torrent Pharmaceuticals Limited); the verapamil FDA label on DailyMed (effective April 6, 2026, Zydus Pharmaceuticals (USA) Inc.).
What does the darifenacin label say about verapamil?
Darifenacin label, drug interactionsNo dosing adjustments are recommended in the presence of moderate CYP3A4 inhibitors (for example, erythromycin, fluconazole, diltiazem and verapamil) [see Dosage and Administration (2) and Clinical Pharmacology (12.3)].
Source: FDA drug label (Darifenacin), Torrent Pharmaceuticals Limited, effective February 10, 2026 (SPL set e84f1ae3-b9a2-4a15-a299-c75373891cc1), via openFDA; the full label on DailyMed
What does the verapamil label say about darifenacin?
Verapamil's label (effective April 6, 2026) and its 3 other brand-application labels do not name darifenacin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Verapamil hydrochloride), Zydus Pharmaceuticals (USA) Inc., effective April 6, 2026 (SPL set e19ab8d8-dae5-489d-9805-7e7407bea06d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Darifenacin | Verapamil | |
|---|---|---|
| Labeled for | Overactive bladder | High blood pressure, Atrial fibrillation, Angina |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.432 per tablet 15 mg tablet | $0.191 per tablet 180 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once