What the FDA labels say about taking them together
Dantrolene and warfarin
Dantrolene's FDA label (Dantrium) of March 10, 2026 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name dantrolene. The dantrolene label: “Binding to plasma proteins is reduced by warfarin and clofibrate and increased by tolbutamide.”
Check it at the source: the dantrolene FDA label on DailyMed (effective August 21, 2026, Par Health USA, LLC); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).
What does the dantrolene label say about warfarin?
Dantrium label (Par Health USA, LLC, March 10, 2026), drug interactionsBinding to plasma proteins is reduced by warfarin and clofibrate and increased by tolbutamide.
Source: FDA drug label (Dantrium, NDA018264), Par Health USA, LLC, effective March 10, 2026 (SPL set 4df35098-8702-46be-ac67-30cfdf1aa570), via openFDA
Source: FDA drug label (dantrolene sodium), Par Health USA, LLC, effective August 21, 2026 (SPL set 11689f56-15e0-4350-b53f-ae96e5994fea), via openFDA; the full label on DailyMed
What does the warfarin label say about dantrolene?
Warfarin's label (effective May 29, 2026) does not name dantrolene in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dantrolene | Warfarin | |
|---|---|---|
| Labeled for | Muscle spasms and spasticity | Blood clots (DVT and PE), Atrial fibrillation |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.409 per capsule 25 mg capsule | $0.093 per tablet 2 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once