What the FDA labels say about taking them together
Dantrolene and isoflurane
Isoflurane's FDA label of January 5, 2026 names dantrolene in its warnings and precautions section; the dantrolene labels PlainMeds reads (3) do not name isoflurane.
Check it at the source: the dantrolene FDA label on DailyMed (effective August 21, 2026, Par Health USA, LLC); the isoflurane FDA label on DailyMed (effective January 5, 2026, Shandong New Time Pharmaceutical Co., Ltd.).
What does the dantrolene label say about isoflurane?
Dantrolene's label (effective August 21, 2026) and its 2 other brand-application labels do not name isoflurane in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (dantrolene sodium), Par Health USA, LLC, effective August 21, 2026 (SPL set 11689f56-15e0-4350-b53f-ae96e5994fea), via openFDA; the full label on DailyMed
What does the isoflurane label say about dantrolene?
Isoflurane label, warnings and precautionsDiscontinue triggering agents, administer intravenous dantrolene sodium, and apply supportive therapies.
Forane label (Baxter Healthcare Corporation, December 9, 2024), warnings and precautionsMalignant Hyperthermia: Malignant hyperthermia may occur, especially in individuals with known or suspected susceptibility based on genetic factors or family history. Discontinue triggering agents, administer intravenous dantrolene sodium, and apply supportive therapies.
Source: FDA drug label (Forane, NDA017624), Baxter Healthcare Corporation, effective December 9, 2024 (SPL set 3d30eb8d-a62e-475f-926b-78ba63bee9c8), via openFDA
Source: FDA drug label (Isoflurane), Shandong New Time Pharmaceutical Co., Ltd., effective January 5, 2026 (SPL set 662ceaf6-650b-4dea-bbee-652f46426024), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dantrolene | Isoflurane | |
|---|---|---|
| Labeled for | Muscle spasms and spasticity | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.409 per capsule 25 mg capsule | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once