What the FDA labels say about taking them together
Cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil and warfarin
Cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil's FDA label of February 4, 2025 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil. The cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil label: “Monitor international normalized ratio (INR) upon coadministration of warfarin with STRIBILD.”
Check it at the source: the cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil FDA label on DailyMed (effective February 4, 2025, Gilead Sciences, Inc.); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).
What does the cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil label say about warfarin?
Cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil label, drug interactionsConcomitant Drug Class/Drug Name: warfarin; Effect on Concentration ↑=Increase, ↓=Decrease: Effect on warfarin unknown; Clinical Comment: Monitor international normalized ratio (INR) upon coadministration of warfarin with STRIBILD.
Source: FDA drug label (Stribild), Gilead Sciences, Inc., effective February 4, 2025 (SPL set 74ae2a93-b267-444c-8f0f-a2a6522260ee), via openFDA; the full label on DailyMed
What does the warfarin label say about cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil?
Warfarin's label (effective May 29, 2026) does not name cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil | Warfarin | |
|---|---|---|
| Labeled for | HIV | Blood clots (DVT and PE), Atrial fibrillation |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $150.14 per tablet Stribild tablet | $0.093 per tablet 2 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once