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What the FDA labels say about taking them together

Cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil and nicardipine

Cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil's FDA label of February 4, 2025 names nicardipine in its drug interactions section; the nicardipine labels PlainMeds reads (2) do not name cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil. The cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil label: “Clinical monitoring is recommended upon coadministration of calcium channel blockers with STRIBILD.”

Check it at the source: the cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil FDA label on DailyMed (effective February 4, 2025, Gilead Sciences, Inc.); the nicardipine FDA label on DailyMed (effective August 24, 2024, Hikma Pharmaceuticals USA Inc.).

What does the cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil label say about nicardipine?

Cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil label, drug interactions

Concomitant Drug Class/Drug Name: Calcium Channel Blockers: e.g., amlodipine diltiazem felodipine nicardipine nifedipine verapamil; Effect on Concentration ↑=Increase, ↓=Decrease: ↑ calcium channel blockers; Clinical Comment: Clinical monitoring is recommended upon coadministration of calcium channel blockers with STRIBILD.

Source: FDA drug label (Stribild), Gilead Sciences, Inc., effective February 4, 2025 (SPL set 74ae2a93-b267-444c-8f0f-a2a6522260ee), via openFDA; the full label on DailyMed

What does the nicardipine label say about cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil?

Nicardipine's label (effective August 24, 2024) and its 1 other brand-application label do not name cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Nicardipine Hydrochloride), Hikma Pharmaceuticals USA Inc., effective August 24, 2024 (SPL set 18fb1c2b-0c1e-436c-a5b6-d4840b5da228), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil generic labelers
25Nicardipine generic labelers
Cobicistat, elvitegravir, emtricitabine and tenofovir disoproxilNicardipine
Labeled forHIVHigh blood pressure, Angina
Boxed warningYesNo
Pharmacy cost (NADAC)$150.14 per tablet Stribild tablet$1.12 per capsule 20 mg capsule
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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