What the FDA labels say about taking them together
Clonidine and verapamil
Clonidine's FDA label of March 30, 2026 names verapamil in its drug interactions section, and verapamil's label names clonidine too.
Check it at the source: the clonidine FDA label on DailyMed (effective March 30, 2026, Unichem Pharmaceuticals (USA), Inc.); the verapamil FDA label on DailyMed (effective April 6, 2026, Zydus Pharmaceuticals (USA) Inc.).
What does the clonidine label say about verapamil?
Clonidine label, drug interactionsSinus bradycardia resulting in hospitalization and pacemaker insertion has been reported in association with the use of clonidine concomitantly with diltiazem or verapamil.
Source: FDA drug label (clonidine hydrochloride), Unichem Pharmaceuticals (USA), Inc., effective March 30, 2026 (SPL set 21bfa28f-20df-43fd-bb80-b720d3b40696), via openFDA; the full label on DailyMed
What does the verapamil label say about clonidine?
Verapamil label, drug interactionsSinus bradycardia resulting in hospitalization and pacemaker insertion has been reported in association with the use of clonidine concurrently with verapamil.
Source: FDA drug label (Verapamil Hydrochloride, NDA019614), Wilshire Pharmaceuticals, Inc., effective November 27, 2024 (SPL set f9399858-fd7a-4b73-8759-3e5bf3af2666), via openFDA
Source: FDA drug label (Verapamil hydrochloride), Zydus Pharmaceuticals (USA) Inc., effective April 6, 2026 (SPL set e19ab8d8-dae5-489d-9805-7e7407bea06d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Clonidine | Verapamil | |
|---|---|---|
| Labeled for | High blood pressure, ADHD, Pain | High blood pressure, Atrial fibrillation, Angina |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0241 per tablet 0.1 mg tablet | $0.191 per tablet 180 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once