Clonidine · larger labeled portfolio than Brimonidine Ophthalmic
SPL labels Clonidine + Brimonidine Ophthalmic as minor; Clonidine 25 / Brimonidine Ophthalmic 1 in that band.
Mechanism on file: Both medications work in a similar way to lower blood pressure, which may cause an additive effect when used together.
FDA SPL severity: Minor
Clonidine + Brimonidine Ophthalmic · SPL mechanism field
Both medications work in a similar way to lower blood pressure, which may cause an additive effect when used together.
Minor band excerpt · Clonidine with Brimonidine Ophthalmic
( 7.2 ) Tricyclic antidepressants may potentially blunt the hypotensive effect of systemic clonidine. 7.3 Tricyclic Antidepressants Tricyclic antidepressants have been reported to blunt the hypotensive effect of systemic clonidine.
Clonidine · 29 SPL pairs (broader portfolio than Brimonidine Ophthalmic)
- Amiodarone minor
- Amitriptyline minor
- Atenolol minor
- Brimonidine/Timolol minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.