What the FDA labels say about taking them together
Cisplatin and furosemide
Furosemide's FDA label of September 30, 2025 names cisplatin in its drug interactions section; the cisplatin label PlainMeds reads does not name furosemide. The furosemide label: “There is a risk of ototoxic effects if cisplatin and LASIX are given concomitantly.”
Check it at the source: the cisplatin FDA label on DailyMed (effective September 16, 2021, WG Critical Care, LLC); the furosemide FDA label on DailyMed (effective September 30, 2025, Validus Pharmaceuticals LLC).
What does the cisplatin label say about furosemide?
Cisplatin's label (effective September 16, 2021) does not name furosemide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (CISplatin), NDA018057 (Hq Spclt Pharma), as published by WG Critical Care, LLC, effective September 16, 2021 (SPL set 2bf8d2fb-80c8-401d-8e9b-d58463f5e954), via openFDA; the full label on DailyMed
What does the furosemide label say about cisplatin?
Furosemide label, drug interactionsThere is a risk of ototoxic effects if cisplatin and LASIX are given concomitantly.
Furosemide label (Hikma Pharmaceuticals USA Inc., March 10, 2025), drug interactionsAvoid combination ( 7.1 ) Salicylates: Risk of salicylate toxicity ( 7.1 ) Cisplatin and nephrotoxic drugs:
Source: FDA drug label (Furosemide, NDA018267), Hikma Pharmaceuticals USA Inc., effective March 10, 2025 (SPL set ddfc41a9-37d4-49c1-bbf3-969a98cd649c), via openFDA
Source: FDA drug label (Lasix), Validus Pharmaceuticals LLC, effective September 30, 2025 (SPL set 2c9b4d8f-0770-482d-a9e6-9c616a440b1a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cisplatin | Furosemide | |
|---|---|---|
| Labeled for | n/a | Heart failure, High blood pressure, Edema (fluid retention) |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $0.490 per mL 20 mg/2 mL vial |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once