What the FDA labels say about taking them together
Ciprofloxacin and pentoxifylline
Pentoxifylline's FDA label of May 15, 2026 names ciprofloxacin in its drug interactions section; the ciprofloxacin labels PlainMeds reads (3) do not name pentoxifylline. The pentoxifylline label: “Concomitant administration of strong CYP1A2 inhibitors may increase the exposure to pentoxifylline (see ADVERSE REACTIONS).”
Check it at the source: the ciprofloxacin FDA label on DailyMed (effective March 2, 2026, Bayer HealthCare Pharmaceuticals Inc.); the pentoxifylline FDA label on DailyMed (effective May 15, 2026, Rising Pharma Holdings, Inc.).
What does the ciprofloxacin label say about pentoxifylline?
Ciprofloxacin's label (effective March 2, 2026) and its 2 other brand-application labels do not name pentoxifylline in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cipro), Bayer HealthCare Pharmaceuticals Inc., effective March 2, 2026 (SPL set 888dc7f9-ad9c-4c00-8d50-8ddfd9bd27c0), via openFDA; the full label on DailyMed
What does the pentoxifylline label say about ciprofloxacin?
Pentoxifylline label, drug interactionsConcomitant administration of strong CYP1A2 inhibitors (including e.g., ciprofloxacin or fluvoxamine) may increase the exposure to pentoxifylline (see ADVERSE REACTIONS).
Source: FDA drug label (Pentoxifylline), Rising Pharma Holdings, Inc., effective May 15, 2026 (SPL set cd840a2c-2a0e-4b2b-84ff-a0406bb6fa37), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ciprofloxacin | Pentoxifylline | |
|---|---|---|
| Labeled for | Diarrhea, Urinary tract infections, Bacterial infections | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.123 per tablet 500 mg tablet | $0.227 per tablet 400 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once