What the FDA labels say about taking them together
Cimetidine and labetalol
Labetalol's FDA label of March 2, 2026 names cimetidine in its drug interactions section; the cimetidine label PlainMeds reads does not name labetalol. The labetalol label: “Cimetidine has been shown to increase the bioavailability of labetalol hydrochloride.”
Check it at the source: the cimetidine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.); the labetalol FDA label on DailyMed (effective March 2, 2026, Zydus Pharmaceuticals USA Inc.).
What does the cimetidine label say about labetalol?
Cimetidine's label (effective July 15, 2026) does not name labetalol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cimetidine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set 06c0a509-026f-44e0-9975-a94a8de51d43), via openFDA; the full label on DailyMed
What does the labetalol label say about cimetidine?
Labetalol label, drug interactionsCimetidine has been shown to increase the bioavailability of labetalol hydrochloride.
Source: FDA drug label (Labetalol Hydrochloride), Zydus Pharmaceuticals USA Inc., effective March 2, 2026 (SPL set 5942a5a8-c3c1-4ecb-921e-9bc92393bdf8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cimetidine | Labetalol | |
|---|---|---|
| Labeled for | Acid reflux and ulcers | High blood pressure |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.236 per tablet 300 mg tablet | $0.215 per tablet 300 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once