Diltiazem · more major-labeled pairs than Cilostazol
SPL labels Cilostazol + Diltiazem as minor; Cilostazol 7 / Diltiazem 35 in that band.
Mechanism on file: Diltiazem slows down the liver's ability to process cilostazol, which leads to higher amounts of the drug staying in your bloodstream. This increases the risk of side effects from cilostazol.
FDA SPL severity: Minor
Cilostazol + Diltiazem · SPL mechanism field
Diltiazem slows down the liver's ability to process cilostazol, which leads to higher amounts of the drug staying in your bloodstream. This increases the risk of side effects from cilostazol.
Minor band excerpt · Cilostazol with Diltiazem
Reduce cilostazol tablets dose ( 2.2 , 7.1 ) 7.1 Inhibitors of CYP3A4 or CYP2C19 Inhibitors of CYP3A4 Coadministration of strong (e.g., ketoconazole) and moderate (e.g., erythromycin, diltiazem and grapefruit juice) CYP3A4 inhibitors can increase exposure to cilostazol.
Cilostazol · 7 minor + 8 total pairs
- Erythromycin minor
- Itraconazole minor
- Ketoconazole minor
- Nirmatrelvir/Ritonavir minor
Diltiazem · 4 major-labeled pairs (vs Cilostazol's 0)
- Amiodarone minor
- Buspirone minor
- Carbamazepine minor
- Carvedilol minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.