What the FDA labels say about taking them together
Chlorpromazine and milsaperidone
Milsaperidone's FDA label of February 27, 2026 names chlorpromazine in its warnings and precautions section; the chlorpromazine label PlainMeds reads does not name milsaperidone.
Check it at the source: the chlorpromazine FDA label on DailyMed (effective May 12, 2026, Amneal Pharmaceuticals NY LLC); the milsaperidone FDA label on DailyMed (effective February 27, 2026, Vanda Pharmaceuticals Inc.).
What does the chlorpromazine label say about milsaperidone?
Chlorpromazine's label (effective May 12, 2026) does not name milsaperidone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (CHLORPROMAZINE HYDROCHLORIDE), Amneal Pharmaceuticals NY LLC, effective May 12, 2026 (SPL set aa086a21-de85-4b03-af58-49b70acf8cf0), via openFDA; the full label on DailyMed
What does the milsaperidone label say about chlorpromazine?
Milsaperidone label, warnings and precautionsSteps to Prevent or Mitigate Clinically Significant Adverse Reactions or Risks Associated with QTc Interval Prolongation The concomitant use of BYSANTI should be avoided with other drugs that prolong the QTc interval including Class 1A antiarrhythmics (e.g., quinidine, procainamide) or Class III antiarrhythmics (e.g., amiodarone, sotalol), antipsychotic drugs that prolong the QTc interval (e.g., chlorpromazine, thioridazine), antibiotics that prolong the QTc interval (e.g., gatifloxacin, moxifloxacin), or any other class of drugs known to prolong the QTc interval (e.g., pentamidine, levomethadyl acetate, methadone).
Source: FDA drug label (BYSANTI), Vanda Pharmaceuticals Inc., effective February 27, 2026 (SPL set 254a1c01-4a4c-4bdd-85d6-1f23f2e4e6f8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Chlorpromazine | Milsaperidone | |
|---|---|---|
| Labeled for | Schizophrenia, Nausea and vomiting | Schizophrenia, Bipolar disorder |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.552 per tablet 100 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once