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What the FDA labels say about taking them together

Chlorpromazine and magnesium sulfate/potassium chloride/sodium sulfate

Magnesium sulfate/potassium chloride/sodium sulfate's FDA label of January 31, 2026 names chlorpromazine in its drug interactions section; the chlorpromazine label PlainMeds reads does not name magnesium sulfate/potassium chloride/sodium sulfate. The magnesium sulfate/potassium chloride/sodium sulfate label: “Administer tetracycline and fluoroquinolone antibiotics, iron, digoxin, chlorpromazine, and penicillamine at least 2 hours before and not less than 6 hours after administration of each dose of SUTAB to avoid chelation …”

Check it at the source: the chlorpromazine FDA label on DailyMed (effective May 12, 2026, Amneal Pharmaceuticals NY LLC); the magnesium sulfate/potassium chloride/sodium sulfate FDA label on DailyMed (effective January 31, 2026, Azurity Pharmaceuticals, Inc.).

What does the chlorpromazine label say about magnesium sulfate/potassium chloride/sodium sulfate?

Chlorpromazine's label (effective May 12, 2026) does not name magnesium sulfate/potassium chloride/sodium sulfate in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (CHLORPROMAZINE HYDROCHLORIDE), Amneal Pharmaceuticals NY LLC, effective May 12, 2026 (SPL set aa086a21-de85-4b03-af58-49b70acf8cf0), via openFDA; the full label on DailyMed

What does the magnesium sulfate/potassium chloride/sodium sulfate label say about chlorpromazine?

Magnesium sulfate/potassium chloride/sodium sulfate label, drug interactions

Administer tetracycline and fluoroquinolone antibiotics, iron, digoxin, chlorpromazine, and penicillamine at least 2 hours before and not less than 6 hours after administration of each dose of SUTAB to avoid chelation with magnesium.

Source: FDA drug label (SUTAB), Azurity Pharmaceuticals, Inc., effective January 31, 2026 (SPL set c020e973-dccf-4862-999e-17db6209a48a), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

33Chlorpromazine generic labelers
0Magnesium sulfate/potassium chloride/sodium sulfate generic labelers
ChlorpromazineMagnesium sulfate/potassium chloride/sodium sulfate
Labeled forSchizophrenia, Nausea and vomitingn/a
Boxed warningYesNo
Pharmacy cost (NADAC)$0.552 per tablet 100 mg tablet$6.74 per tablet 1.479-0.225-0.188 g tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?