What the FDA labels say about taking them together
Chlorpromazine and macimorelin
Macimorelin's FDA label of February 18, 2026 names chlorpromazine in its drug interactions section; the chlorpromazine label PlainMeds reads does not name macimorelin. The macimorelin label: “DRUG INTERACTIONS 7.1 Drugs that Prolong QT Interval Co-administration of MACRILEN with drugs that prolong the QT interval may lead to development of torsade de pointes-type ventricular tachycardia.”
Check it at the source: the chlorpromazine FDA label on DailyMed (effective May 12, 2026, Amneal Pharmaceuticals NY LLC); the macimorelin FDA label on DailyMed (effective February 18, 2026, Aeterna Zentaris GmbH).
What does the chlorpromazine label say about macimorelin?
Chlorpromazine's label (effective May 12, 2026) does not name macimorelin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (CHLORPROMAZINE HYDROCHLORIDE), Amneal Pharmaceuticals NY LLC, effective May 12, 2026 (SPL set aa086a21-de85-4b03-af58-49b70acf8cf0), via openFDA; the full label on DailyMed
What does the macimorelin label say about chlorpromazine?
Macimorelin label, drug interactionsDRUG INTERACTIONS 7.1 Drugs that Prolong QT Interval Co-administration of MACRILEN with drugs that prolong the QT interval (such as antipsychotic medications (e.g., chlorpromazine, haloperidol, thioridazine, ziprasidone), antibiotics (e.g., moxifloxacin), Class 1A (e.g., quinidine, procainamide) and Class III (e.g., amiodarone, sotalol) antiarrhythmic medications or any other medications known to prolong the QT interval) may lead to development of torsade de pointes-type ventricular tachycardia.
Source: FDA drug label (Macrilen), Aeterna Zentaris GmbH, effective February 18, 2026 (SPL set aeb30f1a-4815-47ae-a2cb-b6b4e26372e1), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Chlorpromazine | Macimorelin | |
|---|---|---|
| Labeled for | Schizophrenia, Nausea and vomiting | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.552 per tablet 100 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once