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What the FDA labels say about taking them together

Chlorpromazine and dextroamphetamine

Dextroamphetamine's FDA label of November 26, 2025 names chlorpromazine in its drug interactions section; the chlorpromazine label PlainMeds reads does not name dextroamphetamine.

Check it at the source: the chlorpromazine FDA label on DailyMed (effective May 12, 2026, Amneal Pharmaceuticals NY LLC); the dextroamphetamine FDA label on DailyMed (effective November 26, 2025, Azurity Pharmaceuticals, Inc.).

What does the chlorpromazine label say about dextroamphetamine?

Chlorpromazine's label (effective May 12, 2026) does not name dextroamphetamine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (CHLORPROMAZINE HYDROCHLORIDE), Amneal Pharmaceuticals NY LLC, effective May 12, 2026 (SPL set aa086a21-de85-4b03-af58-49b70acf8cf0), via openFDA; the full label on DailyMed

What does the dextroamphetamine label say about chlorpromazine?

Dextroamphetamine label, drug interactions

Chlorpromazine Chlorpromazine blocks dopamine and norepinephrine reuptake, thus inhibiting the central stimulant effects of amphetamines, and can be used to treat amphetamine poisoning.

Source: FDA drug label (Zenzedi), Azurity Pharmaceuticals, Inc., effective November 26, 2025 (SPL set d6394df5-f2c9-47eb-b57e-f3e9cfd94f84), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

33Chlorpromazine generic labelers
14Dextroamphetamine generic labelers
ChlorpromazineDextroamphetamine
Labeled forSchizophrenia, Nausea and vomitingADHD
Boxed warningYesYes
Pharmacy cost (NADAC)$0.552 per tablet 100 mg tablet$0.373 per tablet 10 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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