What the FDA labels say about taking them together
Chloramphenicol and glimepiride
Glimepiride's FDA label of May 12, 2025 names chloramphenicol in its drug interactions section; the chloramphenicol label PlainMeds reads does not name glimepiride. The glimepiride label: “… fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid and monoamine oxidase inhibitors.”
Check it at the source: the chloramphenicol FDA label on DailyMed (effective October 10, 2024, Fresenius Kabi USA, LLC); the glimepiride FDA label on DailyMed (effective May 12, 2025, Micro Labs Limited).
What does the chloramphenicol label say about glimepiride?
Chloramphenicol's label (effective October 10, 2024) does not name glimepiride in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Chloramphenicol Sodium Succinate), Fresenius Kabi USA, LLC, effective October 10, 2024 (SPL set aed29594-211d-49ef-813f-131975a8d0e3), via openFDA; the full label on DailyMed
What does the glimepiride label say about chloramphenicol?
Glimepiride label, drug interactions… phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid and monoamine oxidase inhibitors.
Source: FDA drug label (Glimepiride), Micro Labs Limited, effective May 12, 2025 (SPL set 60e9397e-83b9-489e-9683-6f87e458bbaa), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Chloramphenicol | Glimepiride | |
|---|---|---|
| Labeled for | n/a | Type 2 diabetes |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $0.0507 per tablet 4 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once