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What the FDA labels say about taking them together

Ceritinib and warfarin

Ceritinib's FDA label of December 15, 2025 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name ceritinib. The ceritinib label: “CYP2C9 Substrates Ceritinib increased the systemic exposure of a CYP2C9 substrate (warfarin).”

Check it at the source: the ceritinib FDA label on DailyMed (effective December 15, 2025, Novartis Pharmaceuticals Corporation); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the ceritinib label say about warfarin?

Ceritinib label, drug interactions

CYP2C9 Substrates Ceritinib increased the systemic exposure of a CYP2C9 substrate (warfarin) [see Clinical Pharmacology (12.3)].

Source: FDA drug label (ZYKADIA), Novartis Pharmaceuticals Corporation, effective December 15, 2025 (SPL set fff5d805-4ffd-4e8e-8e63-6f129697563e), via openFDA; the full label on DailyMed

What does the warfarin label say about ceritinib?

Warfarin's label (effective May 29, 2026) does not name ceritinib in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Ceritinib generic labelers
19Warfarin generic labelers
CeritinibWarfarin
Labeled forLung cancerBlood clots (DVT and PE), Atrial fibrillation
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?